Therapeutic Applications and Diverse Uses of Vinca rosea in Treating Various Disease Conditions: A Comprehensive Review

Abstract

medicinal plant called Vinca rosea has been used for centuries to cure a number of illnesses. Vincristine and vinblastine, two of its more than 70 alkaloids, have demonstrated considerable promise in the treatment of cancer, diabetes, and other disorders. This review article seeks to condense the most recent information on V. rosea’s applications and usage in the management of various illness situations. There is evidence to support the use of V. rosea and its alkaloids in the treatment of leukemia, lymphoma, and solid tumors due to the substantial research done on its anticancer qualities. The microtubule-inhibiting properties of vincristine and vinblastine are known to cause cell cycle arrest and death in cancer cells. These substances are now utilized to treat a variety of cancers in conjunction with other chemotherapeutic medicines. It has also demonstrated hypoglycemic characteristics, with studies indicating that it may increase insulin production, improve glucose absorption by cells, and prevent hepatic glycogen breakdown. These outcomes could help in the management of diabetes and its consequences. Enhancing memory and cognitive function as well as treating hypertension, are two possible advantages. Its vasodilator actions might result in increased blood flow and lowered blood pressure, while its capacity to boost oxygen delivery to the brain could enhance cognition and memory. It has shown a lot of promise in the treatment of numerous illness situations, including diabetes and cancer. Its effectiveness and safety in the treatment of these disorders need to be further investigated, as well as its potential use in treating additional medical conditions.